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Drug Safety in Acute Porphyria

The databases contain expert assessments of the potential of drugs to trigger attacks of Acute Hepatic Porphyria (Acute Intermittent Porphyria (AIP), Hereditary Coproporphyria (HCP), Variegate Porphyria (VP) & ALAD Deficient Porphyria (ADP)) based on the available evidence. However, this evidence is not always complete, which may lead to some degree of uncertainty. The information in these databases is meant as guidance to health care professionals. It must be made clear that the prescription of drugs to a patient with acute Porphyria is entirely at the risk of the physician in charge.

APF Drug Safety Database       

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The database contains expert assessments of the potential of drugs to provoke attacks of acute Porphyria and is intended for use by health care professionals. Compiled by Bo Zhou and Peter V. Tishler, M. D., Channing Laboratory and Genetics Division, Brigham & Women's Hospital, Boston, MA.

Revision 1 — Spring, 2011

Report a Bad Reaction

If you have an Acute Porphyria and have had a bad reaction to a Medication please report it to us by downloading the Safe/Unsafe Drug Questionnaire Form here, fill it out, and send it to the APF at 4915 St. Elmo Avenue, Suite 105, Bethesda, Maryland 20814, or Fax to: 301-312-8713.

Additional Drug Safety Resources:

NAPOS Drug List (The Norwegian Porphyria Centre's multi-language drug database.)

UK Porphyria Medicines Information Services Safe List​

Mobile Web App: Includes the APF and Nordic (NAPOS) Databases